Old News Articles
The John Lab shows that the Schlemm’s canal is a unique vessel that develops by a novel process called “canalogenesis”. The paper is published in PLOS Biology.
Our discoveries were honored with the Lewis Rudin Glaucoma Prize for the paper: Radiation treatment inhibits monocyte entry into the optic nerve head and prevents neuronal damage in a mouse model of glaucoma. J Clin Invest 122(4):1246–1261. It is a great honor that Dr. Gareth Howell accepted this award on our behalf.
In this article, Dr. John is interviewed and provides advice for young investigators. He is truly appreciative and thankful for this opportunity. He wishes to highlight the contributions of his engineering collaborators, Dr. Pedro Irazoqui and Dr. William Chappell of Purdue University to this research. They are essential for this research, which is not possible without them.
Paper published in Nature Genetics
Howell's award from the American Health Assistance Foundation will support his research to asses the importance of the Endothelin System in glaucoma, specifically its role as a mechanism of neuronal cell death. The research will use a mouse model of heritable glaucoma, concentrating on early stages of the disease, prior to significant neuronal cell loss. Endothlelins are known to influence blood pressure. Howell's work shows that Endothelins change very early on in glaucoma and could even be driving pathogenesis. This work has the potential to lead to improved therapies for human glaucoma.
Simon John invited to lecture at 40th Anniversary Celebration of the National Eye Institute
Simon John invited to lecture at Cardiff University for 125th Anniversary
John awarded Collaborative Innovation Award for work with Purdue engineers on ultra-miniature sensors.
Partridge Foundation grants $1.25 million to John for radiation based neuroprotection
Simon John is one of seven researchers recognized by the Alcon Research Institute of Fort Worth, Texas, for dedicating their lives to enhancing the understanding of vision and eye health. These seven doctors, who were nominated by previous winners and selected by ARI’s independent Scientific Selection Committee, will receive $100,000 in unrestricted grant money from the ARI to continue pursuing their research into the underlying causes of eye disease. They also will be recognized at the ARI’s biennial symposium in 2009, where they will present their research to all of the members of the ARI. (adapted from JAX press release)
Simon John accepts 2005 World Glaucoma Association (WGA) Science Award for radiation paper and his creative and breakthrough body of research on glaucoma
Findings published in The New England Journal of Medicine
Paper published in Science
Important findings published in Proceedings of the National Academy of Sciences
The Cogan Award is presented annually to a researcher of 40 years of age or younger, who has made important and worthwhile contributions to research in ophthalmology or visual science that are directly related to disorders of the human eye or visual system, and who shows substantial promise for future research. Dr. John has been selected to receive this honor for his important contributions in the development, analysis and use of mouse models for genetic and therapeutic studies of glaucoma. Dr. John will receive the award and present the Cogan Lecture on Tuesday, April 27 at the 2004 ARVO Annual Meeting in Fort Lauderdale, Florida. (adapted from JAX press release)
Findings published in Science